Only Orchestra, with its 8-hour intraoral activity and ten special probiotic strains freshens breath while fighting a wide range of oral health problems.

“Melts in your mouth — not in your gut”

With its unique, patent pending, Adherent, Place and Forget, Film-Forming feature, each lozenge time-releases into your mouth its ten strains of dental probiotics over three to eight hours. Therefore you can even use it safely during sleep. Other brands of dental probiotic supplements do not have this long-lasting ability.

Orchestra’s intra-oral adherent lozenges stick discreetly in your mouth, and slowly dissolve over 3 to 8 hours to form a spreadable probiotic film. The film protects its ten dental probiotic strains and keeps them growing within your mouth — not in your gut.

They spread throughout your mouth and colonize various niches: tongue, tonsils, throat, sinuses, teeth, gums, and cheeks. In these locations the probiotic microbes continue to grow and compete against bad dental germs. They crowd out bad, odorous germs and fight them for space to grow.

Over time (3 months or so) with repeated use and good oral hygiene practices, Orchestra’s dental probiotics can shift the population of microbes in your mouth toward better, friendlier microbes. More friendly oral microbes means fewer bad bugs in your mouth, naturally. That’s because bad dental germs make bad odors. And fewer bad germs means a healthier mouth and fresher breath. 

Orchestra^® Dental Probiotics is the first of a new class of multi-use, “Place-and-Forget“, adherent, dental synbiotic dietary supplements.

A synbiotic is a combination of probiotics and prebiotics. Probiotics are defined by the World Health Organization as  “micro-organisms that confer a health benefit on the host when administered properly”. Prebiotics are the preferred foods for the probiotics. Prebiotics keep the probiotics healthy while they are growing and doing their jobs.

“Place and Forget” adherence is the game-changing feature

You place the lozenge in your mouth between a cheek and gums. Within 3 minutes the lozenge adheres discreetly and begins slowly dissolving. Then it feels so comfortable you essentially forget about it. You can even sleep safely with it. The total dissolution process takes between 3 to 8 hours, depending upon whether you use it during the day (3 hrs), or while sleeping (8 hrs).

The lozenges are multi-use, which means you can chew them and use them as a dentifrice and a flossing aid.

Morning breath is caused by nighttime overgrowth of bad dental germs. Most dental germs that cause gum disease and cavities smell bad. By “fighting fire with fire” — pitting good probiotic microbes against pathogenic microbes — we can crowd out and eliminate bad germs that cause most common dental problems. Because you awaken with fresh breath, you know that the bad germs have not been growing all night. Fresh morning breath means that the good probiotics have been growing and inhibiting the bad germs.

In summary — because of the well-known oral-systemic link***, by eliminating bad dental germs, we can break the links between dental problems and systemic problems.  Thus, by having fresher breath in the morning, you have fewer bad dental germs, fewer dental problems, and fewer links to systemic problems.

*** Oral health and systemic disease are intimately related but have remained, sadly, as isolated knowledge communities for decades. … it is noteworthy that bacteria form surface-attached communities on most biological surfaces, including the oral cavity. Biofilm-forming bacteria contribute to periodontal diseases and recent evidences point to roles of these bacteria in systemic diseases as well, with cardiovascular diseases, obesity, and cancer as notable examples. [Sintim HO, Gürsoy UK. Biofilms as “Connectors” for Oral and Systems Medicine: A New Opportunity for Biomarkers, Molecular Targets, and Bacterial Eradication. OMICS : a Journal of Integrative Biology. 2016;20(1):3-11. doi:10.1089/omi.2015.0146. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739346/]

Benefits*

(For verification of listed benefits, please see the references below and visit our Research Page)

* Disclaimer: There’s no guarantee of specific results, and your results can vary. However, please refer to the research reports below that support dental probiotics for oral health.

1. Fresh breath in the morning and hours afterward
2. Fights germs that cause gingivitis
3. Fights tonsil stone formation
4. Fights germs that cause tooth decay
5. Fights germs that cause sore throats and sinusitis
6. Better dental checkups
7. Saves money at the dentist

References:

1) Burton, J.P. and Chilcott, C.N. and Moore, C.J. and Speiser, G. and Tagg, J.R., A preliminary study of the effect of probiotic Streptococcus salivarius K12 on oral malodour parameters, Journal of Applied Microbiology, volume 100, number 4, Blackwell Publishing Ltd, url = http://dx.doi.org/10.1111/j.1365-2672.2006.02837.x

2) International Journal of Oral Science (2012) 4, 55–63; doi:10.1038/ijos.2012.39; published online 22 June 2012 —http://www.nature.com/ijos/journal/v4/n2/full/ijos201239a.html#abs

3) Otolaryngol Head Neck Surg. 2009 Sep;141(3):316-21. doi: 10.1016/j.otohns.2009.05.019.; Tonsillolith: not just a stone but a living biofilm.; Stoodley P1, Debeer D, Longwell M, Nistico L, Hall-Stoodley L, Wenig B, Krespi YP.

4) Arch Microbiol. 2014 Aug;196(8):601-9. doi: 10.1007/s00203-014-0998-7. Epub 2014 Jun 12.; A comparative study of the effect of probiotics on cariogenic biofilm model for preventing dental caries.; Lee SH1, Kim YJ.

5) Fiedler T, Riani C, Koczan D, Standar K, Kreikemeyer B, Podbielski A. Protective Mechanisms of Respiratory Tract Streptococci against Streptococcus pyogenes Biofilm Formation and Epithelial Cell Infection. Applied and Environmental Microbiology. 2013;79(4):1265-1276. doi:10.1128/AEM.03350-12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568619/

and also…

Di Pierro F, Colombo M, Zanvit A, Risso P, Rottoli AS. Use of Streptococcus salivarius K12 in the prevention of streptococcal and viral pharyngotonsillitis in children. Drug, Healthcare and Patient Safety. 2014;6:15-20. doi:10.2147/DHPS.S59665. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928062/#

6) In his book, “Dental Caries, A Treatable Infection”, Dr. Walter Loesche from the University of Michigan, calculated in 1973 that the adult human mouth contains 20 billion bacteria in dental plaque, and those 20 billion birth100 billion into saliva every 24 hours. “Dental Caries: A Treatable Infection”, Loesche, W.J. , {https://books.google.com/books?id=Oy9qAAAAMAAJ}, 1993, ADQ Publications